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Subject Area

Anesthesiology

Article Type

Original Study

Abstract

Objectives: The current study was designed to evaluate the role of norepinephrine infusion in maintaining hemodynamics stable in patients undergoing caesarean section Background: Hypotension commonly occurred after spinal anaesthesia and this is caused by sympathetic system inhibition. Methods: Forty female patients undergoing caesarean section were divided into two groups. Group 1 received norepinephrine infusion and group 2 received bolus norepinephrine. Blood pressure, heart rate, cardiac index, stroke volume and systemic vascular resistance were recorded as a baseline and every 10 minutes after intrathecal injection. Results: The mean arterial blood pressure showed a significant reduction in group 2 compared to group 1 at all times of measurement (P < 0.001). Both stroke volume and cardiac index revealed a significant increase in group 1 compared to group 2 (P < 0.001 and > 0.003 respectively). There was no significant difference between both groups as regard systemic vascular resistance, heart rate, thoracic volume variation as well APGAR score at 5 min and 10 min after delivery. Conclusion: Norepinephrine infusion when compared with boluses of 5 μg norepinephrine is superior in maintaining blood pressure, stroke volume and cardiac index after spinal anaesthesia in caesarean section without adverse effects on the baby.

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