Article Type

Original Study


Objective The aim of the study was to estimate the frequency of prediabetes in Egyptian patients with chronic hepatitis C virus (HCV) infection. Background Chronic HCV infection is an important risk factor for insulin resistance (IR) and prediabetes. Patients and methods This study was performed on 50 patients with chronic HCV infection. They included 38 men and 12 women; their age ranged from 20 to 61 years. They were categorized into two groups according to presence or absence of IR, and 25 healthy volunteers of matched age, sex, and BMI were enrolled as the control group. IR was measured by Homeostasis Model Assessment of Insulin Resistance (HOMA-IR). Results In all, 64% of HCV patients were prediabetic with HOMA-IR value greater than 2. Conclusion Chronic HCV patients should be screened regularly for IR.