Article Type

Original Study


Objective The aim of the present study was to determine whether ankle peak systolic velocity (APSV) can predict healing of diabetic foot lesions. Background Problems associated with the diabetic foot are prevalent worldwide. Diabetic foot lesions contribute significantly toward the morbidity and mortality of patients with diabetes mellitus. This study was carried out to evaluate the APSV as a predictor of healing in diabetic foot lesions. Patients and methods Diabetic patients referred to the General Surgery Department of Menoufia University were included in the study. Patients were included if they had foot lesions, such as ulcers, gangrene, or tissue necrosis, and had no palpable pedal pulses. End points were healed, healing, and nonhealing or amputation. In total, 50 diabetic foot patients were included in the study. All of them were subjected to the following: an assessment of full history; physical examination, including foot examination through peripheral pulses including Doppler examination, measurement of APSV, and ankle-brachial index; and routine investigations. Results Twenty-four patients reached the end point of adequate healing or complete healing. On the other hand, 26 patients had nonhealing lesions. The APSV was significantly higher in patients with healed or healing lesions compared with the patients with nonhealed lesions: 57.8 ± 12.72 versus 24.9 ± 9.55 cm/s (P < 0.001). At a cut-off point of 40 cm/s, the APSV showed a sensitivity of 90.91%, a specificity of 100%, a positive predictive value of 100%, and a negative predictive value of 92.3%, with a diagnostic accuracy of 97.4% in predicting the healing of diabetic foot lesions. There was a significant difference between the APSV before and after revascularization: 23.4 ± 6.5 versus 58.8 ± 12.3 cm/s (P < 0.001). Conclusion APSV could predict the healing of diabetic foot lesions with a high degree of accuracy in this group of patients.