Article Type

Original Study


Objective The purpose of this study is to evaluate the efficacy of fibrin glue and fascia lata graft as a substitute for dural repair in postoperative cerebrospinal fluid (CSF) leak after cranial surgery. Background Postoperative CSF leakage is a common complication after many cranial and spinal operations. Several methods are used for repair of dural tears to stop CSF leak; one of these methods is to use fibrin glue with autologous graft - for example, fascia lata - for repair. Materials and methods A total of 12 cases with postoperative CSF leak after cranial surgery were observed and managed in the period from June 2010 to December 2012. In all, four cases were meningiomas and eight cases were gliomas. Male-to-female ratio was 5 : 7 and mean age was 56.8 years. All cases underwent secondary surgery to manage the CSF leak by fascia lata graft and fibrin glue. Mean duration of follow-up was 9.8 months (range 6-20 months). Computed tomography brain with and without contrast was performed to determine the presence of CSF leaks between 2 weeks and 3 months after surgery. Results No CSF fistula was found in all patients. No adverse effects or complications such as wound infection or neurological impairment were encountered postoperatively. Follow-up computed tomography brain revealed no evidence of CSF leakage. Conclusion The use of fascia lata graft and fibrin glue is a useful and effective method in controlling CSF leakage after cranial surgery.