Article Type

Original Study


Objective The aim of this study was to assess the efficacy of thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI). Background The idea of an occluding thrombus as an etiology for ST-elevation myocardial infarction (STEMI) and its dissolution as a treatment had been around since the 1950s. Patients and methods The study included 70 patients with STEMI undergoing PPCI within 12 h from symptoms. These patients were divided equally into two groups (35 patients each): TA group and standard PPCI (SP) group. Primary endpoints were ST-segment resolution 90 min after procedure and thrombolysis in myocardial infarction flow and myocardial blush grade at the end of procedure. Secondary endpoint was in-hospital major adverse cardiovascular effects. Results ST-segment resolution more than 70%, that is, complete reperfusion, was seen in 42.9% of patients in the TA group in comparison with 8.6% in the SP group (P < 0.005). Myocardial blush grade more than or equal to 2 was seen in 91.4% in TA group in comparison with 54.3% in SP group (P < 0.005). We reported death of three patients in the SP group; however, this did not reach statistical significance (P = 0.120). Conclusion TA has significantly improved the reperfusion in patients with STEMI and significantly decreased the incidence of no reflow. Thus, we recommend TA as a routine procedure in PPCI.